⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18571024 | 0.64 | — | — | |
| SCHEMBL14706767 | 0.58 | — | — | |
| SCHEMBL28167119 | 0.56 | — | — | |
| SCHEMBL3078296 | 0.56 | — | — | |
| SCHEMBL7681851 | 0.56 | — | — | |
| SCHEMBL7681855 | 0.56 | — | — | |
| SCHEMBL2941820 | 0.56 | — | — | |
| Ammonia Solution, Strong SCHEMBL3830975 | 0.54 | — | — | |
| SCHEMBL3069575 | 0.54 | — | — | |
| SCHEMBL9500691 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230302150-A1 | ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF | AMBRX, INC. (US) | 2023-09-28 | — | — | US | disclosed |
| US-10954270-B2 | Compositions containing, methods involving, and uses of non-natural amino acid linked dolastatin derivatives | AMBRX, INC. (US) | 2021-03-23 | — | — | US | disclosed |
| US-20200360525-A1 | Modified Relaxin Polypeptides and Their Uses | AMBRX, INC. | 2020-11-19 | — | — | US | disclosed |
| US-10800856-B2 | Prostate-specific membrane antigen antibody drug conjugates | AMBRX, INC. (US) | 2020-10-13 | — | — | US | disclosed |
| US-10377805-B2 | Modified FGF-21 polypeptides comprising non-naturally encoding amino acids and their uses | AMBRX, INC. (US) | 2019-08-13 | — | — | US | disclosed |
| US-9738724-B2 | Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use | SUTRO BIOPHARMA, INC. (US) | 2017-08-22 | — | — | US | disclosed |
| US-9637441-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2017-05-02 | — | — | US | disclosed |