Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22837347 | 0.81 | POLB (0.50) | BTN3A1POLBALDH1A1TSHRMEN1 | |
| SCHEMBL18801782 | 0.79 | BTN3A1 (0.69) | BTN3A1POLBALDH1A1TSHRMEN1 | |
| SCHEMBL22837346 | 0.79 | POLB (0.48) | BTN3A1POLBALDH1A1TSHRMEN1 | |
| SCHEMBL16587319 | 0.79 | BTN3A1 (0.69) | BTN3A1POLBALDH1A1TSHRMEN1 | |
| SCHEMBL13522954 | 0.79 | BTN3A1 (0.69) | BTN3A1POLBALDH1A1TSHRMEN1 | |
| SCHEMBL16926802 | 0.79 | BTN3A1 (0.69) | BTN3A1POLBALDH1A1TSHRMEN1 | |
| SCHEMBL19986747 | 0.79 | BTN3A1 (0.69) | BTN3A1POLBALDH1A1TSHRMEN1 | |
| SCHEMBL16015978 | 0.77 | BTN3A1 (0.60) | BTN3A1POLBALDH1A1TSHRMEN1 | |
| SCHEMBL12746449 | 0.74 | BTN3A1 (0.58) | BTN3A1POLBALDH1A1TSHRMEN1 | |
| SCHEMBL18583602 | 0.74 | BTN3A1 (0.58) | BTN3A1POLBALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2710019-B1 | PROCESSES AND INTERMEDIATES FOR PREPARING ANTI-HIV AGENTS | GILEAD SCIENCES INC (US) | 2017-05-03 | — | — | EP | disclosed |