SCHEMBL18801992

SCHEMBL18801992

CCOC(=O)C(C)N[P@](=O)(CC)Oc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 12/20 0.66
LMNA P02545 1/20 0.45
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 1/20 0.42
POLB P06746 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ELANE P08246 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
MMP8 P22894 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16587332 1.00 BTN3A1 (0.66) BTN3A1LMNATDP1MEN1KMT2A
SCHEMBL16587335 1.00 BTN3A1 (0.66) BTN3A1LMNATDP1MEN1KMT2A
SCHEMBL14042804 1.00 BTN3A1 (0.66) BTN3A1LMNATDP1MEN1KMT2A
SCHEMBL16587337 1.00 BTN3A1 (0.66) BTN3A1LMNATDP1MEN1KMT2A
SCHEMBL16587334 1.00 BTN3A1 (0.66) BTN3A1LMNATDP1MEN1KMT2A
SCHEMBL16587333 1.00 BTN3A1 (0.66) BTN3A1LMNATDP1MEN1KMT2A
SCHEMBL13522954 0.92 BTN3A1 (0.69) BTN3A1LMNATDP1MEN1KMT2A
SCHEMBL19986747 0.92 BTN3A1 (0.69) BTN3A1LMNATDP1MEN1KMT2A
SCHEMBL16926802 0.92 BTN3A1 (0.69) BTN3A1LMNATDP1MEN1KMT2A
SCHEMBL18801782 0.92 BTN3A1 (0.69) BTN3A1LMNATDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2710019-B1 PROCESSES AND INTERMEDIATES FOR PREPARING ANTI-HIV AGENTS GILEAD SCIENCES INC (US) 2017-05-03 EP disclosed