Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CDC42 | P60953 | 1/20 | 0.36 |
| ▸ | RAC1 | P63000 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18806041 | 0.95 | ELANE (0.36) | ELANEAKR1C3AKR1C2KMT2AATM | |
| SCHEMBL20172068 | 0.90 | AKR1C3 (0.39) | ELANEAKR1C3AKR1C2KMT2AATM | |
| SCHEMBL20172060 | 0.85 | TDP1 (0.44) | AKR1C3AKR1C2TDP1L3MBTL1PTGS2 | |
| SCHEMBL18806020 | 0.84 | ELANE (0.43) | ELANEKMT2AATML3MBTL1PTGS2 | |
| SCHEMBL20172059 | 0.83 | AKR1C3 (0.32) | AKR1C3AKR1C2TDP1L3MBTL1PTGS2 | |
| SCHEMBL18806039 | 0.81 | ELANE (0.41) | ELANEKMT2AATMTDP1PTGS2 | |
| SCHEMBL18806043 | 0.80 | APP (0.44) | ELANEAKR1C3AKR1C2KMT2APTGS2 | |
| SCHEMBL18806022 | 0.80 | APP (0.41) | ELANEAKR1C3AKR1C2KMT2APTGS2 | |
| SCHEMBL29405364 | 0.80 | ELANE (0.41) | ELANEAKR1C3AKR1C2KMT2AATM | |
| SCHEMBL18806023 | 0.79 | AKR1C3 (0.39) | ELANEAKR1C3AKR1C2KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11312909-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2022-04-26 | — | — | US | disclosed |
| US-20170121606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | GMBH, MERCK PATENT (DE) | 2017-05-04 | — | — | US | disclosed |
| US-20170121606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | GMBH, MERCK PATENT (DE) | 2017-05-04 | — | — | US | disclosed |
| EP-3162875-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2017-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11312909-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | VCL, LCP1, MAP1LC3C | ELANE 766/4885AKR1C3 4186/4885AKR1C2 4227/4885 |
| US-20170121606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, LCP1, MAP1LC3C | ELANE 719/4885AKR1C3 3918/4885AKR1C2 3967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.