Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.61 |
| ▸ | ALB | P02768 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 12/20 | 0.58 |
| ▸ | CA1 | P00915 | 11/20 | 0.58 |
| ▸ | CA2 | P00918 | 11/20 | 0.58 |
| ▸ | CA12 | O43570 | 6/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529844 | 1.00 | FOLH1 (0.61) | FOLH1ALBCA9CA1CA2 | |
| SCHEMBL31380586 | 1.00 | FOLH1 (0.61) | FOLH1ALBCA9CA1CA2 | |
| SCHEMBL10060089 | 1.00 | FOLH1 (0.61) | FOLH1ALBCA9CA1CA2 | |
| SCHEMBL19389433 | 0.96 | FOLH1 (0.58) | FOLH1ALBCA9CA1CA2 | |
| SCHEMBL22100260 | 0.95 | FOLH1 (0.59) | FOLH1ALBCA9CA1CA2 | |
| SCHEMBL13012837 | 0.93 | CA9 (0.60) | FOLH1ALBCA9CA1CA2 | |
| SCHEMBL24403901 | 0.91 | FOLH1 (0.55) | FOLH1ALBCA9CA1CA2 | |
| SCHEMBL20843781 | 0.90 | FOLH1 (0.56) | FOLH1ALBCA9CA1CA2 | |
| SCHEMBL17245299 | 0.90 | FOLH1 (0.56) | FOLH1ALBCA9CA1CA2 | |
| SCHEMBL13062332 | 0.90 | CA9 (0.57) | FOLH1ALBCA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222617-B1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | UNIV JOHNS HOPKINS (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-3222617-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | The Johns Hopkins University (US) | 2017-09-27 | — | — | EP | disclosed |
| EP-2408755-B1 | Urea-based peptide compounds useful for detecting inter alia prostate cancer | UNIV JOHNS HOPKINS (US) | 2017-05-03 | — | — | EP | disclosed |