SCHEMBL18808262

SCHEMBL18808262

C/C(I)=C1\CC(C)NC1=O

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
BRD4 O60885 3/20 0.32
CREBBP Q92793 2/20 0.32
EP300 Q09472 1/20 0.32
CDC7 O00311 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL509355 0.69
SCHEMBL3336466 0.67
SCHEMBL357257 0.66
SCHEMBL12160740 0.66
SCHEMBL20669542 0.64 TSHR (0.40) TSHRMEN1KMT2ABRD4CREBBP
SCHEMBL20614486 0.63 CREBBP (0.52) TSHRMEN1KMT2ABRD4CREBBP
SCHEMBL9492156 0.61 FUCA1 (0.31)
SCHEMBL31190485 0.60 HTT (0.34) TSHRBRD4CREBBPEP300
SCHEMBL21470711 0.60 TSHR (0.60) TSHRBRD4CREBBPCDC7
SCHEMBL23863601 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3163367-A1 LIQUID CRYSTAL DISPLAY ELEMENT Nissan Chemical Industries, Ltd. (JP) 2017-05-03 EP disclosed