Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 11/20 | 0.58 |
| ▸ | AVPR1A | P37288 | 11/20 | 0.58 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | TRPC5 | Q9UL62 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15124816 | 0.86 | AVPR2 (0.59) | AVPR2AVPR1ASLC6A2OPRK1 | |
| SCHEMBL6927568 | 0.83 | AVPR2 (0.77) | AVPR2AVPR1A | |
| SCHEMBL6930246 | 0.81 | AVPR2 (0.66) | AVPR2AVPR1A | |
| SCHEMBL18808598 | 0.80 | AVPR2 (0.60) | AVPR2AVPR1A | |
| SCHEMBL18808719 | 0.79 | AVPR2 (0.59) | AVPR2AVPR1A | |
| SCHEMBL18808822 | 0.76 | AVPR2 (0.56) | AVPR2AVPR1ASLC6A2OPRK1 | |
| SCHEMBL6929509 | 0.76 | AVPR2 (0.63) | AVPR2AVPR1A | |
| SCHEMBL19577975 | 0.74 | AVPR2 (0.57) | AVPR2AVPR1ASLC6A2OPRK1 | |
| SCHEMBL6929422 | 0.73 | AVPR2 (0.63) | AVPR2AVPR1ASLC6A2OPRK1 | |
| SCHEMBL18808855 | 0.73 | AVPR2 (0.63) | AVPR2AVPR1ASLC6A2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539326-B1 | BISARYL-BONDED ARYLTRIAZOLONES AND USE THEREOF | BAYER IP GMBH (DE) | 2017-05-03 | — | — | EP | disclosed |