Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17453371 | 0.88 | CYP3A4 (0.40) | — | |
| SCHEMBL16112908 | 0.75 | CYP3A4 (0.42) | — | |
| SCHEMBL16112897 | 0.73 | CYP3A4 (0.41) | — | |
| SCHEMBL16133453 | 0.73 | CNR1 (0.40) | CNR2CNR1 | |
| SCHEMBL19309893 | 0.72 | MAPT (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL16113159 | 0.72 | CYP3A4 (0.38) | — | |
| SCHEMBL16133806 | 0.72 | CYP3A4 (0.40) | — | |
| SCHEMBL18809559 | 0.71 | CYP3A4 (0.36) | — | |
| SCHEMBL18809631 | 0.70 | CYP3A4 (0.43) | CNR2CNR1 | |
| SCHEMBL16133773 | 0.67 | CYP3A4 (0.42) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970174-B1 | FUSED FURANS FOR THE TREATMENT OF HEPATITIS C | BRISTOL MYERS SQUIBB CO (US) | 2017-05-03 | — | — | EP | disclosed |