Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1881558 | 1.00 | ABCG2 (0.71) | ABCG2CYP1A1CYP1B1CYP1A2CYP2D6 | |
| SCHEMBL2744097 | 0.88 | ABCG2 (0.73) | ABCG2CYP1A1CYP1B1CYP1A2CYP2D6 | |
| SCHEMBL2743991 | 0.88 | ABCG2 (0.73) | ABCG2CYP1A1CYP1B1CYP1A2CYP2D6 | |
| SCHEMBL9907023 | 0.87 | ABCG2 (0.64) | ABCG2CYP1A1CYP1B1CYP1A2CYP2D6 | |
| SCHEMBL26046380 | 0.87 | KDM4E (0.57) | ABCG2CYP1A1CYP1B1CYP1A2CYP2D6 | |
| SCHEMBL1877092 | 0.87 | KDM4E (0.57) | ABCG2CYP1A1CYP1B1CYP1A2CYP2D6 | |
| SCHEMBL1877093 | 0.87 | KDM4E (0.57) | ABCG2CYP1A1CYP1B1CYP1A2CYP2D6 | |
| SCHEMBL285232 | 0.86 | ABCG2 (0.71) | ABCG2CYP1A1CYP1B1CYP1A2CYP2D6 | |
| SCHEMBL30560976 | 0.86 | ABCG2 (0.71) | ABCG2CYP1A1CYP1B1CYP1A2CYP2D6 | |
| SCHEMBL285231 | 0.86 | ABCG2 (0.71) | ABCG2CYP1A1CYP1B1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939674-B2 | Process for producing an aromatic unsaturated compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-10 | — | — | US | disclosed |
| US-7700642-B2 | Process for producing an aromatic unsaturated compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20090111999-A1 | PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20080221337-A1 | Process for Producing an Aromatic Unsaturated Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-09-11 | — | — | US | disclosed |
| EP-1666440-A1 | METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2006-06-07 | — | — | EP | disclosed |
| EP-0402469-B1 | CATECHOL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATION CONTAINING SAME | TERUMO CORP (JP) | 1994-06-01 | — | — | EP | disclosed |
| EP-0402469-A1 | CATECHOL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATION CONTAINING SAME | TERUMO KABUSHIKI KAISHA (JP) | 1990-12-19 | — | — | EP | disclosed |
| US-4927958-A | ANTIULCER | HOFFMANN-LA ROCHE INC. (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0282897-A2 | Ethynyl- and ethenylstyryl ketones | F. HOFFMANN-LA ROCHE AG (CH) | 1988-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221337-A1 | Process for Producing an Aromatic Unsaturated Compound | AHR, AR, ARSA | ABCG2 1037/4885CYP1A1 4/4885CYP1B1 13/4885 |
| US-20090111999-A1 | PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND | AHR, AR, ARSA | ABCG2 1037/4885CYP1A1 4/4885CYP1B1 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.