Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.50 |
| ▸ | RNF168 | Q8IYW5 | 1/20 | 0.49 |
| ▸ | NOXO1 | Q8NFA2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18788822 | 1.00 | TLR7 (0.50) | TLR7RNF168NOXO1PKMFLT1 | |
| SCHEMBL18811466 | 0.94 | NOXO1 (0.46) | TLR7RNF168NOXO1PKMFLT1 | |
| SCHEMBL22030816 | 0.85 | TLR7 (0.60) | TLR7 | |
| SCHEMBL18818638 | 0.85 | TLR7 (0.60) | TLR7 | |
| SCHEMBL18788718 | 0.84 | TLR7 (0.57) | TLR7 | |
| SCHEMBL18788753 | 0.84 | TLR7 (0.57) | TLR7 | |
| SCHEMBL23169773 | 0.83 | TLR7 (0.63) | TLR7 | |
| SCHEMBL23220196 | 0.83 | TLR7 (0.64) | TLR7 | |
| SCHEMBL18788786 | 0.83 | TLR7 (0.63) | TLR7 | |
| SCHEMBL18788758 | 0.83 | TLR7 (0.63) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017072662-A1 | ANTIBODY CONJUGATES COMPRISING TOLL-LIKE RECEPTOR AGONIST | NOVARTIS AG (CH) | 2017-05-04 | — | — | WO | disclosed |