Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.30 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.30 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28413259 | 0.98 | DYRK1A (0.34) | DYRK1AIRAK4MAPK10JAK1JAK3 | |
| SCHEMBL18536681 | 0.84 | GBA1 (0.36) | IRAK4MAPK10HTR2C | |
| SCHEMBL2809677 | 0.82 | HSD17B10 (0.36) | HTR2C | |
| Hydrochloric Acid SCHEMBL28410160 | 0.80 | HSD17B10 (0.35) | HTR2C | |
| SCHEMBL1528492 | 0.69 | HTR2C (0.37) | HTR2C | |
| SCHEMBL1528578 | 0.68 | HTR2C (0.34) | HTR2C | |
| SCHEMBL785776 | 0.68 | POLB (0.48) | HTR2C | |
| SCHEMBL18818630 | 0.68 | GRM5 (0.46) | MAPK10 | |
| Hydrochloric Acid SCHEMBL2874635 | 0.67 | HTR2C (0.36) | HTR2C | |
| Hydrochloric Acid SCHEMBL16060483 | 0.67 | HTR2C (0.33) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017071636-A1 | PHTHALAZINE KETONE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-05-04 | — | — | WO | disclosed |