Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18820353 | 0.98 | NISCH (0.41) | NISCHHTR1DCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11183418 | 0.81 | NISCH (0.44) | NISCHHTR1DCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11187718 | 0.78 | NISCH (0.46) | NISCHHTR1DCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11181538 | 0.77 | CYP3A4 (0.43) | NISCHHTR1DCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11183396 | 0.76 | CYP3A4 (0.46) | NISCHHTR1DCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11177536 | 0.76 | CYP3A4 (0.46) | NISCHHTR1DCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11188523 | 0.76 | CYP3A4 (0.46) | NISCHHTR1DCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11187375 | 0.76 | CYP3A4 (0.46) | NISCHHTR1DCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11180762 | 0.76 | CYP3A4 (0.46) | NISCHHTR1DCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11180285 | 0.76 | CYP3A4 (0.46) | NISCHHTR1DCYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368643-B1 | LUBRICATING OIL COMPOSITIONS CONTAINING AMIDINE ANTIOXIDANTS | CHEVRON ORONITE CO (US) | 2019-11-20 | — | — | EP | disclosed |
| US-9752092-B2 | Lubricating oil compositions containing amidine antioxidants | CHEVRON ORONITE COMPANY LLC (US) | 2017-09-05 | — | — | US | disclosed |
| US-20170121625-A1 | LUBRICATING OIL COMPOSITIONS CONTAINING AMIDINE ANTIOXIDANTS | CHEVRON ORONITE COMPANY LLC | 2017-05-04 | — | — | US | disclosed |