Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.34 |
| ▸ | ACE | P12821 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795113 | 0.84 | SLC1A3 (0.49) | SLC1A3NOS1SLC7A5CYP3A4GRIA1 | |
| SCHEMBL10769499 | 0.84 | SLC1A3 (0.49) | SLC1A3NOS1SLC7A5CYP3A4GRIA1 | |
| SCHEMBL8932777 | 0.84 | SLC1A3 (0.49) | SLC1A3NOS1SLC7A5CYP3A4GRIA1 | |
| SCHEMBL18822339 | 0.79 | ACE2 (0.41) | ACE2ACE | |
| SCHEMBL10397323 | 0.78 | SLC1A3 (0.47) | SLC1A3NOS1SLC7A5CYP3A4GRIA1 | |
| SCHEMBL10397324 | 0.78 | SLC1A3 (0.47) | SLC1A3NOS1SLC7A5CYP3A4GRIA1 | |
| SCHEMBL743804 | 0.77 | SLC1A3 (0.58) | SLC1A3NOS1SLC7A5CYP3A4GRIA1 | |
| SCHEMBL743805 | 0.77 | SLC1A3 (0.58) | SLC1A3NOS1SLC7A5CYP3A4GRIA1 | |
| SCHEMBL10398089 | 0.76 | SLC1A3 (0.44) | SLC1A3NOS1SLC7A5CYP3A4GRIA1 | |
| SCHEMBL10397191 | 0.76 | CYP11B1 (0.55) | SLC1A3NOS1SLC7A5HSD17B10ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190055279-A1 | NOVEL POLYPEPTIDES WITH IMPROVED PROTEOLYTIC STABILITY, AND METHODS OF PREPARING AND USING SAME | TUFTS UNIVERSITY (US) | 2019-02-21 | — | — | US | disclosed |
| WO-2017075505-A2 | NOVEL POLYPEPTIDES WITH IMPROVED PROTEOLYTIC STABILITY, AND METHODS OF PREPARING AND USING SAME | TUFTS UNIVERSITY (US) | 2017-05-04 | — | — | WO | disclosed |
| WO-2017075522-A2 | GLP-2 POLYPEPTIDES WITH IMPROVED PROTEOLYTIC STABILITY, AND METHODS OF PREPARING AND USING SAME | TUFTS UNIVERSITY (US) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190055279-A1 | NOVEL POLYPEPTIDES WITH IMPROVED PROTEOLYTIC STABILITY, AND METHODS OF PREPARING AND USING SAME | PTMS, ANPEP, DNPEP | SLC1A3 2929/4885NOS1 3473/4885SLC7A5 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.