Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22231278 | 0.86 | TSHR (0.58) | TSHRTHRBALDH1A1 | |
| SCHEMBL14511610 | 0.81 | TSHR (0.62) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL23493920 | 0.81 | TSHR (0.68) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL5879383 | 0.81 | TSHR (0.62) | TSHRTHRBALDH1A1 | |
| SCHEMBL4384013 | 0.81 | TSHR (0.53) | TSHRTHRB | |
| SCHEMBL4209201 | 0.81 | TDP1 (0.38) | TSHRALDH1A1TDP1 | |
| SCHEMBL13114701 | 0.79 | TSHR (0.54) | TSHRTHRBALDH1A1 | |
| SCHEMBL24562 | 0.78 | TSHR (1.00) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL7776912 | 0.77 | TSHR (0.56) | TSHRTHRBALDH1A1 | |
| SCHEMBL15807757 | 0.77 | TSHR (0.56) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802730-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-04-19 | — | — | EP | disclosed |
| EP-3529332-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2020-11-25 | — | — | EP | disclosed |
| EP-3529333-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2020-11-25 | — | — | EP | disclosed |
| US-10570335-B2 | Liquid crystal medium containing polymerisable compounds | MERCK PATETN GMBH (DE) | 2020-02-25 | — | — | US | disclosed |
| EP-3368637-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-08-07 | — | — | EP | disclosed |
| US-20180187080-A1 | LIQUID CRYSTAL MEDIUM CONTAINING POLYMERISABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2018-07-05 | — | — | US | disclosed |
| US-20180187080-A1 | LIQUID CRYSTAL MEDIUM CONTAINING POLYMERISABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2018-07-05 | — | — | US | disclosed |
| US-20180179446-A1 | LIQUID CRYSTAL MEDIUM CONTAINING POLYMERISABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2018-06-28 | — | — | US | disclosed |
| WO-2017071793-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2017-05-04 | — | — | WO | disclosed |