Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 19/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1879532 | 0.88 | IGF1R (0.51) | IGF1R | |
| SCHEMBL1878749 | 0.88 | IGF1R (0.46) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL4160707 | 0.87 | IGF1R (0.47) | IGF1R | |
| SCHEMBL1879194 | 0.86 | IGF1R (0.48) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL1876987 | 0.86 | IGF1R (0.54) | IGF1R | |
| SCHEMBL4149811 | 0.85 | IGF1R (0.46) | IGF1R | |
| SCHEMBL1876994 | 0.84 | IGF1R (0.47) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL1876890 | 0.84 | IGF1R (0.55) | IGF1R | |
| SCHEMBL12636517 | 0.83 | IGF1R (0.51) | IGF1R | |
| SCHEMBL1879195 | 0.83 | IGF1R (0.46) | IGF1RPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935819-B2 | Cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors | AVENTIS PHARMA S.A. (FR) | 2011-05-03 | — | — | US | disclosed |