Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 17/20 | 0.63 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | PRF1 | P14222 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16065348 | 1.00 | CTSC (0.63) | CTSCCTSKPRF1 | |
| SCHEMBL14821847 | 0.89 | CTSC (0.60) | CTSCCTSK | |
| SCHEMBL16078784 | 0.88 | CTSC (0.62) | CTSCCTSK | |
| SCHEMBL16064124 | 0.88 | CTSC (0.62) | CTSCCTSK | |
| SCHEMBL16065136 | 0.87 | CTSC (0.65) | CTSCCTSK | |
| SCHEMBL18828637 | 0.87 | CTSC (0.65) | CTSCCTSK | |
| SCHEMBL16065326 | 0.86 | CTSC (0.66) | CTSCCTSK | |
| SCHEMBL18828550 | 0.86 | CTSC (0.66) | CTSCCTSK | |
| SCHEMBL16065135 | 0.86 | CTSC (0.65) | CTSCCTSK | |
| SCHEMBL18828763 | 0.86 | CTSC (0.65) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970228-B1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2017-05-10 | — | — | EP | disclosed |