Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 4/20 | 0.52 |
| ▸ | SGK1 | O00141 | 1/20 | 0.45 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 5/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.40 |
| ▸ | IL1RN | P18510 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL590443 | 0.83 | CDC7 (0.52) | CDC7SGK1KDM4ENPSR1RXFP1 | |
| SCHEMBL18812718 | 0.82 | CDC7 (0.50) | CDC7SGK1KDM4EMAP2K4AURKA | |
| SCHEMBL18828996 | 0.80 | MAPT (0.57) | CDC7ALDH1A1AURKAAURKB | |
| SCHEMBL29516430 | 0.76 | DYRK1A (0.52) | CDC7SGK1KDM4ERXFP1MAPK14 | |
| SCHEMBL24287487 | 0.76 | DYRK1A (0.52) | CDC7SGK1KDM4ERXFP1MAPK14 | |
| SCHEMBL4502136 | 0.74 | GSK3B (0.60) | CDC7SGK1KDM4ENPSR1RXFP1 | |
| SCHEMBL28155841 | 0.74 | MAPK10 (0.49) | CDC7ALDH1A1 | |
| SCHEMBL18932045 | 0.74 | MAPK10 (0.52) | CDC7ALDH1A1 | |
| SCHEMBL18812703 | 0.73 | FLT3 (0.49) | CDC7ITKALDH1A1MAP2K4AURKA | |
| SCHEMBL22722926 | 0.71 | DYRK1A (0.46) | CDC7MAPK14AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3165523-A2 | COMPOSITION FOR INDUCING CELL REPROGRAMMING | Gwangju Institute of Science and Technology (KR) | 2017-05-10 | — | — | EP | disclosed |