⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3497463 | 1.00 | — | — | |
| SCHEMBL3497861 | 1.00 | — | — | |
| SCHEMBL13370390 | 0.76 | — | — | |
| SCHEMBL4257793 | 0.74 | — | — | |
| SCHEMBL18977593 | 0.72 | — | — | |
| SCHEMBL3499347 | 0.71 | — | — | |
| SCHEMBL5470241 | 0.71 | — | — | |
| SCHEMBL1164637 | 0.71 | — | — | |
| SCHEMBL14850834 | 0.69 | — | — | |
| SCHEMBL11883270 | 0.67 | PTGS1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-219441617-U | Tubular reaction device for 2, 4-dihydroxy-3, 3-dimethylbutyronitrile | 湖北楚维药业有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-114773295-A | Method for synthesizing pantolactone | 重庆医药高等专科学校 | 2022-07-22 | — | — | CN | claimed |
| CN-110498781-B | Method for synthesizing D, L-pantolactone | 上海东庚化工技术有限公司 | 2021-12-10 | — | — | CN | claimed |
| EP-0528256-B1 | D-2,4-dihydroxy-3,3-dimethylbutyronitrile, its production and use and process for production of D-pantolactone, D-2,4-dihydroxy-3,3-dimethylbutyramide and D-pantothenic acid | DEGUSSA (DE) | 1996-09-25 | — | — | EP | claimed |
| US-5326702-A | Hydrolysis of the nitrile | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-07-05 | — | — | US | claimed |
| EP-0528256-A1 | D-2,4-dihydroxy-3,3-dimethylbutyronitrile, its production and use and process for production of D-pantolactone, D-2,4-dihydroxy-3,3-dimethylbutyramide and D-pantothenic acid | DEGUSSA AG (DE) | 1993-02-24 | — | — | EP | claimed |
| CN-117700380-A | Synthesis method of DL-pantothenic acid lactone | 重庆市化工研究院有限公司 | 2024-03-15 | — | — | CN | disclosed |
| US-20230348941-A1 | METHODS FOR PREPARING PANTOIC ACID, PANTOTHENIC ACID AND PANTHENOL AS WELL AS SALTS THEREOF | MINT BIOTECHNOLOGIES CO., LTD. (CN) | 2023-11-02 | — | — | US | disclosed |
| CN-219441617-U | Tubular reaction device for 2, 4-dihydroxy-3, 3-dimethylbutyronitrile | 湖北楚维药业有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-219441617-U | Tubular reaction device for 2, 4-dihydroxy-3, 3-dimethylbutyronitrile | 湖北楚维药业有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-219441617-U | Tubular reaction device for 2, 4-dihydroxy-3, 3-dimethylbutyronitrile | 湖北楚维药业有限公司 | 2023-08-01 | — | — | CN | disclosed |
| EP-4174185-A1 | METHODS FOR PREPARING PANTOIC ACID, PANTOTHENIC ACID AND PANTHENOL AS WELL AS SALTS THEREOF | Mint BioTech Ltd. (CN) | 2023-05-03 | — | — | EP | disclosed |
| CN-114773295-A | Method for synthesizing pantolactone | 重庆医药高等专科学校 | 2022-07-22 | — | — | CN | disclosed |
| US-5508181-A | REACTING AN ALPHA-HYDROXYNITRILE (OR MIXTURE WITH AN ALDEHYDE) WITH HYDROGEN CYANIDE IN PRESENCE OF PHOSPHITE OR HYPOPHOSPHITE IONS | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0666320-A2 | Process for producing alpha-hydroxy acid or alpha-hydroxyamide by microorganisms | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5326702-A | Hydrolysis of the nitrile | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0528256-A1 | D-2,4-dihydroxy-3,3-dimethylbutyronitrile, its production and use and process for production of D-pantolactone, D-2,4-dihydroxy-3,3-dimethylbutyramide and D-pantothenic acid | DEGUSSA AG (DE) | 1993-02-24 | — | — | EP | disclosed |
| EP-0528256-A1 | D-2,4-dihydroxy-3,3-dimethylbutyronitrile, its production and use and process for production of D-pantolactone, D-2,4-dihydroxy-3,3-dimethylbutyramide and D-pantothenic acid | DEGUSSA AG (DE) | 1993-02-24 | — | — | EP | disclosed |
| EP-0528256-A1 | D-2,4-dihydroxy-3,3-dimethylbutyronitrile, its production and use and process for production of D-pantolactone, D-2,4-dihydroxy-3,3-dimethylbutyramide and D-pantothenic acid | DEGUSSA AG (DE) | 1993-02-24 | — | — | EP | disclosed |
| US-3935256-A | Process for the production of the calcium salt of pantothenic acid | THOMPSON-HAYWARD CHEM. CO. (US) | 1976-01-27 | — | — | US | disclosed |