Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDUA | P35475 | 4/20 | 0.69 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.33 |
| ▸ | IGF2R | P11717 | 1/20 | 0.33 |
| ▸ | FGF2 | P09038 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | LRAT | O95237 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18820169 | 1.00 | IDUA (0.69) | IDUASUCNR1LGALS3IGF2RFGF2 | |
| SCHEMBL19784458 | 1.00 | IDUA (0.69) | IDUASUCNR1LGALS3IGF2RFGF2 | |
| SCHEMBL18830785 | 1.00 | IDUA (0.69) | IDUASUCNR1LGALS3IGF2RFGF2 | |
| SCHEMBL18820168 | 1.00 | IDUA (0.69) | IDUASUCNR1LGALS3IGF2RFGF2 | |
| SCHEMBL18820167 | 1.00 | IDUA (0.69) | IDUASUCNR1LGALS3IGF2RFGF2 | |
| SCHEMBL18820183 | 1.00 | IDUA (0.69) | IDUASUCNR1LGALS3IGF2RFGF2 | |
| SCHEMBL18820166 | 1.00 | IDUA (0.69) | IDUASUCNR1LGALS3IGF2RFGF2 | |
| SCHEMBL18831829 | 1.00 | IDUA (0.69) | IDUASUCNR1LGALS3IGF2RFGF2 | |
| SCHEMBL20888700 | 1.00 | IDUA (0.69) | IDUASUCNR1LGALS3IGF2RFGF2 | |
| SCHEMBL19784383 | 1.00 | IDUA (0.69) | IDUASUCNR1LGALS3IGF2RFGF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3165532-A2 | AURISTATIN DERIVATIVES, LINKER-DRUGS AND LIGAND-DRUG CONJUGATES | Industrial Technology Research Institute (TW) | 2017-05-10 | — | — | EP | disclosed |