Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21317952 | 0.91 | CD274 (0.36) | MRGPRX4FFAR4CD274FFAR1 | |
| SCHEMBL20686716 | 0.89 | KDM4E (0.39) | NPC1RAB9APOLBHPGDSMN1; SMN2 | |
| SCHEMBL18831290 | 0.89 | MEN1 (0.37) | MRGPRX4HSD17B10POLBHPGDMAPT | |
| SCHEMBL18831370 | 0.88 | SMN1; SMN2 (0.39) | MRGPRX4NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL20686765 | 0.86 | MRGPRX4 (0.43) | MRGPRX4FFAR4NPC1RAB9ATP53 | |
| SCHEMBL20686688 | 0.84 | MRGPRX4 (0.42) | MRGPRX4FFAR4NPC1RAB9ATP53 | |
| SCHEMBL20686584 | 0.83 | HIF1A (0.38) | MRGPRX4CD274MEN1KMT2A | |
| SCHEMBL18831548 | 0.83 | MRGPRX4 (0.34) | MRGPRX4CD274 | |
| SCHEMBL18749712 | 0.82 | MRGPRX4 (0.46) | MRGPRX4FFAR4NPC1RAB9ATP53 | |
| SCHEMBL18831381 | 0.82 | MRGPRX4 (0.38) | MRGPRX4NPC1ALDH1A1CD274PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900655-B1 | TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2017-05-10 | — | — | EP | disclosed |