Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 17/20 | 0.66 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.63 |
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17411144 | 0.87 | ALK (0.86) | ALKMAPK3EGFR | |
| SCHEMBL24885722 | 0.83 | ALK (0.75) | ALKEGFR | |
| SCHEMBL29618204 | 0.83 | ALK (0.81) | ALKEGFR | |
| SCHEMBL30833027 | 0.82 | ALK (0.62) | ALKMAPK3EGFR | |
| SCHEMBL24620266 | 0.82 | ALK (0.62) | ALKMAPK3EGFR | |
| SCHEMBL18832000 | 0.80 | ALK (0.88) | ALKEGFR | |
| SCHEMBL18831906 | 0.80 | ALK (0.65) | ALKEGFR | |
| SCHEMBL17410920 | 0.79 | ALK (1.00) | ALKEGFR | |
| SCHEMBL29094740 | 0.78 | EGFR (0.76) | ALKEGFR | |
| SCHEMBL17411098 | 0.78 | ALK (1.00) | ALKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3165530-A1 | SPIROCYCLIC ARYL PHOSPHORUS OXIDE AND ARYL PHOSPHORUS SULFIDE | Qilu Pharmaceutical Co., Ltd (CN) | 2017-05-10 | — | — | EP | disclosed |