Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.72 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 8/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 5/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | XBP1 | P17861 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.60 |
| ▸ | BRAF | P15056 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6348692 | 0.88 | BRAF (0.72) | TSHRALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL16028621 | 0.86 | ATM (0.71) | ATMAPOBEC3GTSHRALDH1A1MEN1 | |
| SCHEMBL19375412 | 0.86 | ATM (0.71) | ATMAPOBEC3GTSHRALDH1A1MEN1 | |
| SCHEMBL16028820 | 0.86 | ATM (0.71) | ATMAPOBEC3GTSHRALDH1A1MEN1 | |
| SCHEMBL16028236 | 0.83 | ATM (0.67) | ATMAPOBEC3GTSHRALDH1A1MEN1 | |
| SCHEMBL16028826 | 0.82 | TSHR (1.00) | ATMAPOBEC3GTSHRALDH1A1MEN1 | |
| SCHEMBL20652970 | 0.82 | ATM (0.62) | ATMAPOBEC3GTSHRALDH1A1MEN1 | |
| SCHEMBL16028896 | 0.80 | TSHR (0.84) | ATMAPOBEC3GTSHRALDH1A1MEN1 | |
| SCHEMBL5075029 | 0.80 | POLB (0.84) | ATMAPOBEC3GTSHRALDH1A1MEN1 | |
| SCHEMBL16028495 | 0.80 | TSHR (0.67) | ATMAPOBEC3GTSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B3 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2018-08-01 | — | — | EP | disclosed |
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |