Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.93 |
| ▸ | LMNA | P02545 | 3/20 | 0.93 |
| ▸ | CCR1 | P32246 | 3/20 | 0.93 |
| ▸ | CCR5 | P51681 | 3/20 | 0.93 |
| ▸ | CCR8 | P51685 | 3/20 | 0.93 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.93 |
| ▸ | POLB | P06746 | 1/20 | 0.93 |
| ▸ | METAP1 | P53582 | 1/20 | 0.93 |
| ▸ | BLM | P54132 | 1/20 | 0.93 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.93 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.93 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.93 |
| ▸ | NPC1 | O15118 | 6/20 | 0.74 |
| ▸ | TP53 | P04637 | 4/20 | 0.74 |
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL16026844 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL4150988 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29351528 | 0.97 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29907716 | 0.97 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL5922 | 0.97 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL3711450 | 0.97 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL2340917 | 0.93 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL11800041 | 0.93 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL10395611 | 0.93 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL7909040 | 0.93 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010913-B1 | METHOD FOR SUPPRESSING A FRET SIGNAL, FRET SIGNAL SUPPRESSOR AGENTS AND USE IN A METHOD FOR MULTIPLEXING BIOLOGICAL EVENTS | CISBIO BIOASSAYS (FR) | 2017-12-20 | — | — | EP | claimed |
| EP-1810008-A4 | P27 UBIQUITINATION ASSAY AND METHODS OF USE | SIGNAL PHARM LLC (US) | 2008-09-10 | — | — | EP | claimed |
| EP-1810008-A2 | P27 UBIQUITINATION ASSAY AND METHODS OF USE | Signal Pharmaceuticals LLC (US) | 2007-07-25 | — | — | EP | claimed |
| EP-1166119-B1 | HOMOGENEOUS DETECTION AND/OR DETERMINATION METHOD FOR A CHEMICAL OR PHYSICO-CHEMICAL INTERACTION | CIS BIO INT (FR) | 2007-03-14 | — | — | EP | claimed |
| US-20060194262-A1 | P27 ubiquitination assay and methods of use | XU SHUICHAN | 2006-08-31 | — | — | US | claimed |
| WO-2006044747-A2 | P27 UBIQUITINATION ASSAY AND METHODS OF USE | SIGNAL PHARMACEUTICALS, LLC (US) | 2006-04-27 | — | — | WO | claimed |
| CN-110121510-B | Single domain antibodies to programmed cell death (PD-1) | 克雷森多生物制剂有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-110121510-A | SINGLE DOMAIN ANTIBODIES TO PROGRAMMED CELL DEATH (PD-1) | 克雷森多生物制剂有限公司 | 2019-08-13 | — | — | CN | disclosed |
| US-9024022-B2 | Substrates of O6-alkylguanine-DNA alkyltransferase and mutants thereof | CIS BIO INTERNATIONAL (FR) | 2015-05-05 | — | — | US | disclosed |
| EP-2087355-B1 | METHOD FOR THE DETECTION OF POST-TRANSLATIONAL MODIFICATIONS | CISBIO BIOASSAYS (FR) | 2014-09-24 | — | — | EP | disclosed |
| US-8663928-B2 | Method for the detection of post-translational modifications | CIS BIO INTERNATIONAL (FR) | 2014-03-04 | — | — | US | disclosed |
| US-8361715-B2 | Method for suppressing a FRET signal, FRET signal suppressor agents and use in a method for multiplexing biological events | CIS BIO INTERNATIONAL (FR) | 2013-01-29 | — | — | US | disclosed |
| US-8071761-B2 | Substrates for beta-lactamase and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-06 | — | — | US | disclosed |
| EP-0817785-B1 | SUBSTRATES FOR BETA-LACTAMASE AND USES THEREOF | UNIV CALIFORNIA (US) | 2001-04-04 | — | — | EP | disclosed |
| EP-0982398-A1 | Substrates for beta-lactamase and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-03-01 | — | — | EP | disclosed |
| US-5955604-A | Substrates for β-lactamase and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-09-21 | — | — | US | disclosed |
| US-5858676-A | Electrochemiluminescence of rare earth metal chelates | IGEN INTERNATIONAL, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0817785-A2 | SUBSTRATES FOR BETA-LACTAMASE AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996033411-A1 | ELECTROCHEMILUMINESCENCE OF RARE EARTH METAL CHELATES | IGEN, INC. (US) | 1996-10-24 | — | — | WO | disclosed |
| WO-1996030540-A2 | SUBSTRATES FOR BETA-LACTAMASE AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-10-03 | — | — | WO | disclosed |