SCHEMBL188423

SCHEMBL188423

CCCCO[Si](CC(C)OCC1CO1)(OCCCC)OCCCC

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.49
ALDH1A1 P00352 4/20 0.42
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL188276 0.91 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL2235182 0.88 SMN1; SMN2 (0.49) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL5360247 0.87 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL1132658 0.85 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL11764315 0.85 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL11761440 0.84 SMN1; SMN2 (0.45) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL188407 0.84 SMN1; SMN2 (0.34) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL28063191 0.84 SMN1; SMN2 (0.34) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL5367844 0.84 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL29154143 0.81 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120315486-A1 OPTICAL COATING COMPOSITION THE WALMAN OPTICAL COMPANY (US) 2012-12-13 US claimed
US-20120015191-A1 OPTICAL COATING COMPOSITION THE WALMAN OPTICAL COMPANY (US) 2012-01-19 US claimed
US-7981514-B2 Coating composition yielding abrasion-resistant tintable coatings THE WALMAN OPTICAL COMPANY (US) 2011-07-19 US claimed
US-20100279026-A1 COATING COMPOSITION YIELDING ABRASION-RESISTANT TINTABLE COATINGS THE WALMAN OPTICAL COMPANY (US) 2010-11-04 US claimed
US-20100190010-A1 OPTICAL COATING COMPOSITION THE WALMAN OPTICAL COMPANY (US) 2010-07-29 US claimed
US-20100068539-A1 OPTICAL COATING COMPOSITION THE WALMAN OPTICAL COMPANY 2010-03-18 US claimed
US-7514482-B2 Optical coating composition THE WALMAN OPTICAL COMPANY (US) 2009-04-07 US claimed
US-20080311408-A1 Optical Coating Composition THE WALMAN OPTICAL COMPANY (US) 2008-12-18 US claimed
US-20080280144-A1 COATING COMPOSITION YIELDING ABRASION-RESISTANT TINTABLE COATINGS THE WALMAN OPTICAL COMPANY (US) 2008-11-13 US claimed
US-7384695-B2 Coating composition yielding abrasion-resistant tintable coatings THE WALMAN OPTICAL COMPANY (US) 2008-06-10 US claimed
EP-1917296-A1 OPTICAL COATING COMPOSITION The Walman Optical Company (US) 2008-05-07 EP claimed
EP-1226219-B1 COATING COMPOSITION YIELDING ABRASION-RESISTANT TINTABLE COATINGS WALMAN OPTICAL COMPANY (US) 2007-11-21 EP claimed
WO-2007018617-A1 OPTICAL COATING COMPOSITION WALMAN OPTICAL COMPANY, THE (US) 2007-02-15 WO claimed
US-20070021523-A1 Optical coating composition WALMAN OPTICAL COMPANY, THE 2007-01-25 US claimed
US-20060292376-A1 Coating composition yielding abrasion-resistant tintable coatings THE WALMAN OPTICAL COMPANY 2006-12-28 US claimed
US-7037585-B2 Coating composition yielding abrasion-resistant tintable coating THE WALMAN OPTICAL COMPANY (US) 2006-05-02 US claimed
US-20040234789-A1 Coating composition yielding abrasion-resistant tintable coating WALMAN OPTICAL COMPANY, THE 2004-11-25 US claimed
US-6780232-B2 FOR LENSES; HYDROLYSIS PRODUCT OF A EPOXY-FUNCTIONAL ALKOXYSILANE, AN UNSATURATED MONOMER, AND TO REDUCE THE VISCOSITY, AN UNHYDROLYZED EPOXY-FUNCTIONAL ALKOXYSILANE THE WALMAN OPTICAL COMPANY 2004-08-24 US claimed
US-6432191-B1 None US disclosed
US-4026826-A ALKOXYSILANES JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) 1977-05-31 US disclosed