Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TK1 | P04183 | 4/20 | 0.52 |
| ▸ | TYMS | P04818 | 1/20 | 0.51 |
| ▸ | TK2 | O00142 | 2/20 | 0.51 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18848408 | 0.87 | POLB (0.61) | POLBTK1TYMS | |
| SCHEMBL29354298 | 0.85 | POLB (0.64) | POLBTK1TYMSRNASE1 | |
| SCHEMBL16508397 | 0.83 | POLB (0.65) | POLBTK1TYMSRNASE1 | |
| SCHEMBL8529362 | 0.83 | POLB (0.67) | POLBTK1TYMS | |
| SCHEMBL16130860 | 0.83 | POLB (0.67) | POLBTK1TYMS | |
| SCHEMBL19069725 | 0.83 | POLB (0.65) | POLBTK1TYMSRNASE1 | |
| SCHEMBL10034052 | 0.83 | POLB (0.65) | POLBTK1TYMSRNASE1 | |
| SCHEMBL19069606 | 0.83 | POLB (0.65) | POLBTK1TYMSRNASE1 | |
| SCHEMBL29456897 | 0.83 | POLB (0.67) | POLBTK1TYMS | |
| Thymidine Monophosphate SCHEMBL8027147 | 0.82 | POLB (0.72) | POLBTK1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170130246-A1 | TRANS-ACTING ELEMENTS FOR INTRACELLULAR DELIVERY OF NUCLEIC ACID SEQUENCES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170130246-A1 | TRANS-ACTING ELEMENTS FOR INTRACELLULAR DELIVERY OF NUCLEIC ACID SEQUENCES | ZYX, TPX2, ZFX | POLB 475/4885TK1 9/4885TYMS 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.