Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.36 |
| ▸ | CNR1 | P21554 | 11/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19934960 | 0.83 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL18516933 | 0.83 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL18681924 | 0.79 | KDM4E (0.44) | CNR2CNR1 | |
| SCHEMBL18522956 | 0.79 | CNR2 (0.39) | CNR2CNR1 | |
| SCHEMBL22023836 | 0.77 | KDM4E (0.42) | CNR2CNR1 | |
| SCHEMBL22601465 | 0.77 | CNR2 (0.38) | CNR2CNR1 | |
| SCHEMBL19619562 | 0.76 | KCNH2 (0.42) | TRPV4 | |
| SCHEMBL21503708 | 0.76 | KCNH2 (0.42) | TRPV4 | |
| SCHEMBL23502540 | 0.76 | CNR2 (0.34) | CNR2CNR1 | |
| SCHEMBL23502537 | 0.76 | CNR2 (0.34) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650379-B2 | Azaindole derivatives as selective histone deacetylase (HDAC) inhibitors and pharmaceutical compositions comprising the same | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2017-05-16 | — | — | US | disclosed |