SCHEMBL18853453

SCHEMBL18853453

c1ccc2cc3c(cc2c1)sc1nc(-n2c4ccccc4c4ccccc42)nc(-n2c4ccccc4c4ccccc42)c13

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.30
▸ ATM Q13315 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16905633 0.86 ELANE (0.39) ELANEKDM4EATML3MBTL1
SCHEMBL18853455 0.82 ELANE (0.32) ELANEKDM4EATML3MBTL1
SCHEMBL18853404 0.80 CYP1A1 (0.33) KDM4EATML3MBTL1
SCHEMBL18852956 0.79 HRH4 (0.33) KDM4EATML3MBTL1
SCHEMBL19163319 0.77 ELANE (0.32) ELANE
SCHEMBL19163327 0.77 ELANE (0.32) ELANE
SCHEMBL18853397 0.77 KDM4E (0.38) KDM4EATML3MBTL1
SCHEMBL18853503 0.76 KDM4E (0.36) KDM4EATML3MBTL1
SCHEMBL18853296 0.76 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL19162843 0.75 ELANE (0.32) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10680190-B2 Organic compound, organic optoelectronic element, and display device SAMSUNG SDI CO., LTD. (KR) 2020-06-09 — — US disclosed
US-20170141331-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE SAMSUNG SDI CO.,LTD. (KR) 2017-05-18 — — US disclosed
US-20170141331-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE SAMSUNG SDI CO.,LTD. (KR) 2017-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170141331-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE OCIAD1, OXER1, OCIAD2 ELANE 3382/4885KDM4E 3232/4885ATM 4486/4885
US-10680190-B2 Organic compound, organic optoelectronic element, and display device OCIAD1, OXER1, OCIAD2 ELANE 3382/4885KDM4E 3232/4885ATM 4486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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