⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580844 | 1.00 | — | — | |
| SCHEMBL971307 | 0.78 | — | — | |
| SCHEMBL29849628 | 0.78 | — | — | |
| SCHEMBL1577450 | 0.72 | — | — | |
| SCHEMBL18343908 | 0.72 | — | — | |
| SCHEMBL24404928 | 0.72 | — | — | |
| SCHEMBL1202805 | 0.72 | — | — | |
| SCHEMBL3361574 | 0.72 | — | — | |
| SCHEMBL20829926 | 0.72 | — | — | |
| SCHEMBL663225 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822887-A | Preparation of difluoropyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1989-04-18 | — | — | US | claimed |
| EP-3887371-B1 | ARYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | HOFFMANN LA ROCHE (CH) | 2023-02-22 | — | — | EP | disclosed |
| EP-3887370-B1 | TRICYCLIC COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |
| CN-110491999-B | Modification method of electron transport layer for organic solar cell | 太原理工大学 | 2022-04-12 | — | — | CN | disclosed |
| US-20210309657-A1 | TRICYCLIC COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2021-10-07 | — | — | US | disclosed |
| US-20210309658-A1 | ARYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2021-10-07 | — | — | US | disclosed |
| EP-3887371-A1 | ARYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | F. Hoffmann-La Roche AG (CH) | 2021-10-06 | — | — | EP | disclosed |
| EP-3887370-A1 | TRICYCLIC COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | F. Hoffmann-La Roche AG (CH) | 2021-10-06 | — | — | EP | disclosed |
| CN-113166144-A | Aryl compounds for the treatment and prevention of bacterial infections | 豪夫迈·罗氏有限公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020109190-A1 | TRICYCLIC COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-04 | — | — | WO | disclosed |
| US-4652650-A | Pyridylaminoalkylamine intermediates | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-03-24 | — | — | US | disclosed |
| US-4565568-A | Pyridyl(oxy/thio)phenoxy compounds, herbicidal compositions and methods | THE DOW CHEMICAL COMPANY (US) | 1986-01-21 | — | — | US | disclosed |
| US-4548940-A | Pyridylaminoalkylaminopyrimidones useful as histamine H1 -antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-10-22 | — | — | US | disclosed |
| EP-0146924-A2 | Preparation of difluorpyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1985-07-03 | — | — | EP | disclosed |
| EP-0112707-A2 | Aminopyrimidinone derivatives as histamine H1-antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1984-07-04 | — | — | EP | disclosed |
| EP-0029123-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED ANILINES, AND SUBSTITUTED ANILINES | BASF Aktiengesellschaft (DE) | 1983-06-08 | — | — | EP | disclosed |
| EP-0029123-A1 | Process for the preparation of substituted anilines, and substituted anilines | BASF Aktiengesellschaft (DE) | 1981-05-27 | — | — | EP | disclosed |
| EP-0013145-A2 | Substituted anilinopyridines, processes for their preparation and intermediates for use therein, compositions and herbicidal use thereof | ICI AUSTRALIA LIMITED (AU) | 1980-07-09 | — | — | EP | disclosed |
| US-4135045-A | PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1979-01-16 | — | — | US | disclosed |
| US-4048415-A | TITANIUM-ALUMINUM COORDINATION CATALYSTS | MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) | 1977-09-13 | — | — | US | disclosed |