Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.88 |
| ▸ | LCK | P06239 | 1/20 | 0.88 |
| ▸ | FYN | P06241 | 1/20 | 0.88 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL22711549 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL9789820 | 1.00 | FFAR3 (0.88) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL28276437 | 1.00 | — | — | |
| Acetic Acid SCHEMBL28321803 | 1.00 | — | — | |
| Acetic Acid SCHEMBL20272820 | 0.94 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL19991644 | 0.94 | — | — | |
| Acetic Acid SCHEMBL8579765 | 0.94 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL135589 | 0.94 | — | — | |
| Acetic Acid SCHEMBL10385154 | 0.94 | — | — | |
| Acetic Acid SCHEMBL10798079 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117623644-A | Gas phase preparation method for growing chalcogenide quantum dots in nano-pore inorganic glass | 中国科学院上海光学精密机械研究所 | 2024-03-01 | — | — | CN | claimed |
| CN-116709890-A | Preparation method of piezoelectric ceramic composite material with Schwarz P structure | 大连海事大学 | 2023-09-05 | — | — | CN | claimed |
| CN-108299964-A | Anti-aging coating of insulation for outdoor box switchyard and preparation method thereof | 河南龙翔电气股份有限公司 | 2018-07-20 | — | — | CN | claimed |
| CN-106189795-A | Insulation aging resistance coating for outdoor box switchyard and preparation method thereof | 安徽罗伯特科技股份有限公司 | 2016-12-07 | — | — | CN | claimed |
| CN-106118432-A | Insulation aging resistance outdoor box switchyard and preparation method thereof | 安徽罗伯特科技股份有限公司 | 2016-11-16 | — | — | CN | claimed |
| CN-117623644-A | Gas phase preparation method for growing chalcogenide quantum dots in nano-pore inorganic glass | 中国科学院上海光学精密机械研究所 | 2024-03-01 | — | — | CN | disclosed |
| CN-116709890-A | Preparation method of piezoelectric ceramic composite material with Schwarz P structure | 大连海事大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-115207830-A | Grouting plugging method for through hole of cable conduit | 江西创可通工程技术有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-112490369-A | Preparation method of semiconductor material, perovskite semiconductor device and preparation method thereof | 北京大学深圳研究生院 | 2021-03-12 | — | — | CN | disclosed |
| CN-109021204-B | A kind of low-heat type polyurethane consolidation by grouting material | 北京瑞诺安科新能源技术有限公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-109021204-A | A kind of low-heat type polyurethane consolidation by grouting material | 北京瑞诺安科新能源技术有限公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-108299964-A | Anti-aging coating of insulation for outdoor box switchyard and preparation method thereof | 河南龙翔电气股份有限公司 | 2018-07-20 | — | — | CN | disclosed |
| EP-1289440-A1 | SELECTIVE PHOTOCOAGULATION | THE GENERAL HOSPITAL CORPORATION (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001091661-A1 | SELECTIVE PHOTOCOAGULATION | THE GENERAL HOSPITAL CORPORATION (US) | 2001-12-06 | — | — | WO | disclosed |
| EP-0858444-A4 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-12-01 | — | — | EP | disclosed |
| EP-0858444-A1 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-08-19 | — | — | EP | disclosed |
| US-5750549-A | ANTIINFLAMMATORY AGENTS OR ANALGESICS | MERCK & CO., INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5672493-A | TRANSDUCTION OF HUMAN FIBROBLAST CELLS WITH SNYDER-THEILEN:FESV, HARVESTING THE FLOATING TRANSDUCED CELLS AND REPLATING; GENE AND SOMATIC CELL THERAPY; ANTICARCINOGENIC AND -TUMOR AGENTS | KOPELOVICH LEVY (US) | 1997-09-30 | — | — | US | disclosed |
| WO-1997014671-A1 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-04-24 | — | — | WO | disclosed |
| US-3957598-A | Metal hydrates and salts of carboxylic acids | MERKL GEORGE | 1976-05-18 | — | — | US | disclosed |