Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15555980 | 0.87 | GAA (0.52) | JAK2GAAGFERMEN1KMT2A | |
| SCHEMBL18856830 | 0.85 | JAK2 (0.50) | JAK2GAAGFERMEN1KMT2A | |
| SCHEMBL15556419 | 0.83 | GAA (0.56) | JAK2GAAGFERMEN1KMT2A | |
| SCHEMBL18755083 | 0.80 | JAK2 (0.56) | JAK2GAAGFERMEN1KMT2A | |
| SCHEMBL18755252 | 0.79 | JAK2 (0.58) | JAK2GAAGFERMEN1KMT2A | |
| SCHEMBL18856733 | 0.79 | JAK2 (1.00) | JAK2GAAGFERMEN1KMT2A | |
| SCHEMBL18856402 | 0.75 | JAK2 (0.76) | JAK2GAAGFERMEN1KMT2A | |
| SCHEMBL18856595 | 0.75 | JAK2 (0.62) | JAK2GAAGFERMEN1KMT2A | |
| SCHEMBL18856585 | 0.74 | JAK2 (0.73) | JAK2GAAGFERMEN1KMT2A | |
| SCHEMBL17394301 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2870143-B1 | TRIAZOLE COMPOUNDS AS ANTIVIRALS | HOFFMANN LA ROCHE (CH) | 2017-05-17 | — | — | EP | disclosed |