Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16014502 | 0.86 | GAA (0.59) | GAAMEN1GFERKMT2AMAPT | |
| SCHEMBL16014545 | 0.80 | — | — | |
| SCHEMBL16471272 | 0.79 | GAA (0.61) | GAAMEN1GFERKMT2AMAPT | |
| SCHEMBL16471273 | 0.77 | GAA (0.63) | GAAMEN1GFERKMT2AMAPT | |
| SCHEMBL18856553 | 0.77 | — | — | |
| SCHEMBL16014331 | 0.77 | — | — | |
| SCHEMBL15544102 | 0.75 | GAA (0.59) | GAAMEN1GFERKMT2AMAPT | |
| SCHEMBL18856773 | 0.75 | GAA (0.59) | GAAMEN1GFERKMT2AMAPT | |
| SCHEMBL16471283 | 0.74 | GAA (0.63) | GAAMEN1GFERKMT2AMAPT | |
| SCHEMBL15606409 | 0.74 | JAK2 (0.70) | GAAMEN1GFERKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2870143-B1 | TRIAZOLE COMPOUNDS AS ANTIVIRALS | HOFFMANN LA ROCHE (CH) | 2017-05-17 | — | — | EP | disclosed |