Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886739 | 0.89 | IGF1R (0.48) | IGF1R | |
| SCHEMBL1894274 | 0.83 | NTRK1 (0.36) | IGF1R | |
| SCHEMBL4098952 | 0.83 | IGF1R (0.41) | IGF1R | |
| SCHEMBL1890569 | 0.82 | IGF1R (0.51) | IGF1R | |
| SCHEMBL1373065 | 0.80 | IGF1R (0.44) | IGF1R | |
| SCHEMBL1881954 | 0.80 | IGF1R (0.47) | IGF1R | |
| SCHEMBL1886688 | 0.79 | IGF1R (0.46) | IGF1R | |
| SCHEMBL1892267 | 0.77 | IGF1R (0.49) | IGF1R | |
| SCHEMBL1887120 | 0.76 | IGF1R (0.51) | IGF1R | |
| SCHEMBL1889267 | 0.76 | NTRK1 (0.37) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947686-B2 | Substituted pyrazolo[4,3-c]pyridine derivatives active as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2011-05-24 | — | — | US | disclosed |