Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16984855 | 1.00 | USP2 (0.57) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL19186356 | 0.89 | USP2 (0.56) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL18258274 | 0.89 | USP2 (0.56) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL18258278 | 0.89 | USP2 (0.56) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL18258279 | 0.89 | USP2 (0.56) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL18258310 | 0.89 | USP2 (0.56) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL18258309 | 0.89 | USP2 (0.56) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL29149997 | 0.86 | USP2 (0.45) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL8336206 | 0.85 | CYP3A4 (0.55) | USP2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL18257799 | 0.84 | USP2 (0.53) | USP2ALDH1A1LMNAALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650365-B2 | Itraconazole analogues and methods of use thereof | UNIVERSITY OF CONNECTICUT (US) | 2017-05-16 | — | — | US | disclosed |