Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | RECQL | P46063 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | BLM | P54132 | 4/20 | 0.58 |
| ▸ | APEX1 | P27695 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MTOR | P42345 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15654040 | 0.88 | RECQL (0.43) | TDP1KDM4EMAPTRECQLLMNA | |
| SCHEMBL28165577 | 0.77 | TDP1 (0.50) | TDP1KDM4EMAPTRECQLLMNA | |
| SCHEMBL7192542 | 0.77 | TDP1 (0.50) | TDP1KDM4EMAPTRECQLLMNA | |
| SCHEMBL20361608 | 0.77 | TDP1 (0.50) | TDP1KDM4EMAPTRECQLLMNA | |
| SCHEMBL278495 | 0.74 | TDP1 (0.67) | TDP1KDM4EMAPTRECQLLMNA | |
| SCHEMBL30516160 | 0.74 | TDP1 (0.67) | TDP1KDM4EMAPTRECQLLMNA | |
| SCHEMBL14293022 | 0.74 | TDP1 (0.67) | TDP1KDM4EMAPTRECQLLMNA | |
| SCHEMBL15973924 | 0.73 | KDM4E (0.43) | TDP1KDM4EMAPTRECQLLMNA | |
| Levonordefrin SCHEMBL14478222 | 0.73 | TDP1 (1.00) | TDP1KDM4EMAPTRECQLLMNA | |
| Levonordefrin SCHEMBL6295856 | 0.73 | TDP1 (1.00) | TDP1KDM4EMAPTRECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168208-A1 | PROCESSES FOR THE PREPARATION OF DIASTEREOMERICALLY AND ENANTIOMERICALLY ENRICHED OXAZOLINES | Quimica Sintetica, S.A. (ES) | 2017-05-17 | — | — | EP | disclosed |