Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30181855 | 0.90 | CTNNB1 (0.44) | PDK2CTNNB1ALDH1A1HPGDLTA4H | |
| SCHEMBL28311629 | 0.90 | ADORA2A (0.44) | PDK2CTNNB1FFAR4LMNAGAA | |
| SCHEMBL15713464 | 0.87 | PDK2 (0.48) | PDK2FFAR4LMNAKMT2ABRD4 | |
| SCHEMBL20222316 | 0.85 | PDK2 (0.40) | PDK2FFAR4NCOA1NCOA3LMNA | |
| SCHEMBL20222311 | 0.85 | PDK2 (0.47) | PDK2FFAR4LMNAKMT2ABRD4 | |
| SCHEMBL20222315 | 0.83 | PDK2 (0.48) | PDK2FFAR4LMNAKMT2ABRD4 | |
| SCHEMBL23463285 | 0.79 | PDK2 (0.37) | PDK2CTNNB1FFAR4ALDH1A1HPGD | |
| SCHEMBL22875765 | 0.78 | PDK2 (0.54) | PDK2THRBTDP1LTA4HTSHR | |
| SCHEMBL7316250 | 0.77 | KMT2A (0.56) | PDK2ALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL29459438 | 0.76 | PDK2 (0.33) | PDK2TDP1FFAR4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10644246-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-05-05 | — | — | US | disclosed |
| US-20170141327-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-05-18 | — | — | US | disclosed |
| US-20170141327-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10644246-B2 | Materials for organic electroluminescent devices | OR10J3, EPCAM, L1CAM | PDK2 1098/4885THRB 4746/4885TDP1 1958/4885 |
| US-20170141327-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EPCAM, L1CAM | PDK2 1098/4885THRB 4746/4885TDP1 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.