Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 13/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
| ▸ | AXL | P30530 | 3/20 | 0.40 |
| ▸ | MERTK | Q12866 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23158685 | 0.91 | CHEK2 (0.53) | FYNCHEK2CHEK1TGFBR1AXL | |
| SCHEMBL18860363 | 0.85 | CHEK2 (0.47) | FYNCHEK2CHEK1TGFBR1AXL | |
| SCHEMBL23158671 | 0.83 | CHEK1 (0.46) | FYNCHEK2CHEK1TGFBR1AXL | |
| SCHEMBL18861342 | 0.83 | CHEK1 (0.46) | FYNCHEK2CHEK1TGFBR1AXL | |
| SCHEMBL18860964 | 0.78 | FYN (0.47) | FYNCHEK2CHEK1TGFBR1AXL | |
| SCHEMBL23158727 | 0.77 | CHEK2 (0.42) | FYNCHEK2CHEK1TGFBR1AXL | |
| SCHEMBL23158702 | 0.72 | CHEK2 (0.53) | FYNCHEK2CHEK1AXLMERTK | |
| SCHEMBL29576661 | 0.70 | FYN (0.76) | FYNCHEK2CHEK1TGFBR1 | |
| SCHEMBL15334401 | 0.70 | FYN (0.76) | FYNCHEK2CHEK1TGFBR1 | |
| SCHEMBL23158688 | 0.69 | AXL (0.51) | FYNCHEK2CHEK1AXLMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168219-B1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP | DAIICHI SANKYO CO LTD (JP) | 2021-03-31 | — | — | EP | disclosed |
| EP-3168219-A1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-05-17 | — | — | EP | disclosed |