Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 6/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.53 |
| ▸ | AXL | P30530 | 9/20 | 0.44 |
| ▸ | MERTK | Q12866 | 8/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23158688 | 0.88 | AXL (0.51) | FYNCHEK2CHEK1AXLMERTK | |
| SCHEMBL23158702 | 0.80 | CHEK2 (0.53) | FYNCHEK2CHEK1AXLMERTK | |
| SCHEMBL18860964 | 0.79 | FYN (0.47) | FYNCHEK2CHEK1AXLMERTK | |
| SCHEMBL23158772 | 0.76 | AXL (0.47) | FYNCHEK2CHEK1AXLMERTK | |
| SCHEMBL23158685 | 0.75 | CHEK2 (0.53) | FYNCHEK2CHEK1AXLMERTK | |
| SCHEMBL30521707 | 0.74 | FYN (1.00) | FYNCHEK2CHEK1TGFBR1 | |
| SCHEMBL18613347 | 0.74 | FYN (1.00) | FYNCHEK2CHEK1TGFBR1 | |
| SCHEMBL18860363 | 0.73 | CHEK2 (0.47) | FYNCHEK2CHEK1AXLMERTK | |
| SCHEMBL18860437 | 0.72 | FYN (0.69) | FYNCHEK2CHEK1TGFBR1 | |
| SCHEMBL21185638 | 0.71 | CHEK2 (0.58) | FYNCHEK2CHEK1AXLMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168219-B1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP | DAIICHI SANKYO CO LTD (JP) | 2021-03-31 | — | — | EP | disclosed |
| EP-3168219-A1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-05-17 | — | — | EP | disclosed |