Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 20/20 | 0.56 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18839603 | 0.91 | MALT1 (0.55) | MALT1BIRC3 | |
| SCHEMBL18839604 | 0.91 | MALT1 (0.55) | MALT1BIRC3 | |
| SCHEMBL29672172 | 0.91 | MALT1 (0.55) | MALT1BIRC3 | |
| SCHEMBL18839679 | 0.83 | MALT1 (0.66) | MALT1BIRC3 | |
| SCHEMBL18839678 | 0.83 | MALT1 (0.66) | MALT1BIRC3 | |
| SCHEMBL17292932 | 0.81 | MALT1 (0.84) | MALT1BIRC3 | |
| SCHEMBL17292930 | 0.81 | MALT1 (0.84) | MALT1BIRC3 | |
| SCHEMBL18839583 | 0.80 | MALT1 (0.64) | MALT1BIRC3 | |
| SCHEMBL18839581 | 0.80 | MALT1 (0.64) | MALT1BIRC3 | |
| SCHEMBL18839565 | 0.78 | MALT1 (0.81) | MALT1BIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017081641-A1 | NOVEL PYRAZOLO PYRIMIDINE DERIVATIVES | NOVARTIS AG (CH) | 2017-05-18 | — | — | WO | disclosed |