Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18864067 | 1.00 | PTGDR2 (0.36) | PTGDR2MAPTDRD2DRD3MRGPRX4 | |
| SCHEMBL18864116 | 1.00 | PTGDR2 (0.36) | PTGDR2MAPTDRD2DRD3MRGPRX4 | |
| SCHEMBL18864020 | 0.80 | MAPT (0.35) | MAPTDRD3MRGPRX4ALDH1A1LMNA | |
| SCHEMBL18864027 | 0.80 | MAPT (0.35) | MAPTDRD3MRGPRX4ALDH1A1LMNA | |
| SCHEMBL18864022 | 0.80 | MAPT (0.35) | MAPTDRD3MRGPRX4ALDH1A1LMNA | |
| SCHEMBL18864137 | 0.79 | DRD4 (0.43) | DRD2DRD3TSHR | |
| SCHEMBL18864155 | 0.79 | DRD4 (0.43) | DRD2DRD3TSHR | |
| SCHEMBL18864135 | 0.79 | DRD4 (0.43) | DRD2DRD3TSHR | |
| SCHEMBL18864029 | 0.78 | POLB (0.39) | MRGPRX4ALDH1A1LMNA | |
| SCHEMBL18864026 | 0.78 | POLB (0.39) | MRGPRX4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145005-A1 | KINASE INHIBITOR | THE UNIVERSITY OF TOKYO (JP) | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145005-A1 | KINASE INHIBITOR | PIM3, PIM1, PIM2 | PTGDR2 4609/4885MAPT 2447/4885DRD2 4629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.