SCHEMBL1886434

SCHEMBL1886434

CCCC(CCCCCC(CCC)N=C=O)N=C=O

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH4 P08319 1/20 0.32
ADH7 P40394 1/20 0.32
CA2 P00918 1/20 0.32
ALDH1A1 P00352 1/20 0.31
GPR84 Q9NQS5 3/20 0.30
FDPS P14324 3/20 0.30
FFAR1 O14842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12464486 0.96 MAPT (0.39) MAPTADH1BADH1CADH1AADH4
SCHEMBL29036640 0.96 MAPT (0.39) MAPTADH1BADH1CADH1AADH4
SCHEMBL6844203 0.96 MAPT (0.39) MAPTADH1BADH1CADH1AADH4
SCHEMBL21722569 0.93 CA1 (0.36) MAPTADH1BADH1CADH1AADH4
SCHEMBL2564972 0.91 MAPT (0.42) MAPTADH1BADH1CADH1AADH4
SCHEMBL21722523 0.91 MAPT (0.42) MAPTADH1BADH1CADH1AADH4
SCHEMBL21722662 0.91 MAPT (0.42) MAPTADH1BADH1CADH1AADH4
SCHEMBL18324263 0.91 MAPT (0.42) MAPTADH1BADH1CADH1AADH4
SCHEMBL11575980 0.91 MAPT (0.42) MAPTADH1BADH1CADH1AADH4
SCHEMBL21722878 0.91 MAPT (0.42) MAPTADH1BADH1CADH1AADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2501744-B1 COMPOSITIONS COMPRISING SILOXANE COPOLYMERS WACKER CHEMIE AG (DE) 2014-03-19 EP disclosed
US-8440770-B2 Compositions comprising siloxane copolymers WACKER CHEMIE AG (DE) 2013-05-14 US disclosed
EP-2507281-A1 CHIPPING-RESISTANT COATING COMPOSITION Kansai Paint Co., Ltd (JP) 2012-10-10 EP disclosed
EP-2501744-A1 COMPOSITIONS COMPRISING SILOXANE COPOLYMERS Wacker Chemie AG (DE) 2012-09-26 EP disclosed
US-20120232217-A1 COMPOSITIONS COMPRISING SILOXANE COPOLYMERS WACKER CHEMIE AG (DE) 2012-09-13 US disclosed
WO-2011068246-A1 CHIPPING-RESISTANT COATING COMPOSITION KANSAI PAINT CO., LTD. (JP) 2011-06-09 WO disclosed
WO-2011061161-A1 COMPOSITIONS COMPRISING SILOXANE COPOLYMERS WACKER CHEMIE AG (DE) 2011-05-26 WO disclosed