Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 9/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 9/20 | 0.43 |
| ▸ | ITGAL | P20701 | 9/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18868524 | 0.85 | ITGB2 (0.53) | HDAC6ITGB2ICAM1ITGAL | |
| SCHEMBL15503295 | 0.83 | ITGB2 (0.58) | ITGB2ICAM1ITGAL | |
| SCHEMBL18362378 | 0.81 | ITGB2 (0.58) | ITGB2ICAM1ITGAL | |
| SCHEMBL18362384 | 0.78 | HDAC6 (0.79) | HDAC6HRH4CA12CA1CA2 | |
| SCHEMBL18868101 | 0.77 | ITGB2 (0.57) | HDAC6ITGB2ICAM1ITGAL | |
| SCHEMBL18885628 | 0.76 | ITGB2 (0.59) | HDAC6ITGB2ICAM1ITGAL | |
| SCHEMBL13894226 | 0.74 | ITGB2 (0.55) | ITGB2ICAM1ITGAL | |
| SCHEMBL18362337 | 0.74 | HDAC6 (0.46) | HDAC6ITGB2ICAM1ITGALSPR | |
| SCHEMBL12062979 | 0.74 | ITGB2 (0.55) | ITGB2ICAM1ITGAL | |
| SCHEMBL23992528 | 0.73 | ITGB2 (0.56) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167886-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | SARcode Bioscience Inc. (US) | 2017-05-17 | — | — | EP | disclosed |