Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.71 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.71 |
| ▸ | ITGAL | P20701 | 20/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16854955 | 0.90 | ITGB2 (0.71) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL18885224 | 0.87 | ITGB2 (0.73) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL12507169 | 0.87 | ITGB2 (0.74) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL13894420 | 0.86 | ITGB2 (0.76) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL18868481 | 0.85 | ITGB2 (0.75) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL17991457 | 0.85 | ITGB2 (0.74) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL13894223 | 0.84 | ITGB2 (0.73) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL18867979 | 0.84 | ITGB2 (0.70) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL28927235 | 0.84 | ITGB2 (0.77) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL22296915 | 0.84 | ITGB2 (0.70) | ITGB2ICAM1ITGALCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3797775-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | Novartis AG (CH) | 2021-03-31 | — | — | EP | disclosed |
| EP-3167886-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | SARcode Bioscience Inc. (US) | 2017-05-17 | — | — | EP | disclosed |