Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL1887097

CCC(C)COCC(C)CC.OCCOCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
MAPK1 P28482 1/20 0.48
ALDH1A1 P00352 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 2/20 0.41
THRB P10828 1/20 0.41
HTT P42858 1/20 0.41
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14193569 0.93 MEN1 (0.50) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL26983262 0.93 MEN1 (0.50) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL1133309 0.93 MEN1 (0.50) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL12019096 0.93 MEN1 (0.50) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL26983264 0.93 MEN1 (0.50) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL25299176 0.93 MEN1 (0.50) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL12452285 0.93 MEN1 (0.50) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL39518 0.93
SCHEMBL14900153 0.93
Water SCHEMBL8616227 0.91 MEN1 (0.48) TSHRMAPK1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7935798-B2 Method for the extraction of intracellular proteins from a fermentation broth DOW GLOBAL TECHNOLOGIES LLC (US) 2011-05-03 US claimed
US-20090023902-A1 Method for the extraction of intracellular proteins from a fermentation broth DOW GLOBAL TECHNOLOGIES LLC 2009-01-22 US claimed
EP-1720897-A2 METHOD FOR THE EXTRACTION OF INTRACELLULAR PROTEINS FROM A FERMENTATION BROTH The Dow Global Technologies Inc. (US) 2006-11-15 EP claimed
WO-2005087791-A2 METHOD FOR THE EXTRACTION OF INTRACELLULAR PROTEINS FROM A FERMENTATION BROTH DOW GLOBAL TECHNOLOGIES INC. (US) 2005-09-22 WO claimed
US-7935798-B2 Method for the extraction of intracellular proteins from a fermentation broth DOW GLOBAL TECHNOLOGIES LLC (US) 2011-05-03 US disclosed
EP-1720897-B1 METHOD FOR THE EXTRACTION OF INTRACELLULAR PROTEINS FROM A FERMENTATION BROTH DOW GLOBAL TECHNOLOGIES INC (US) 2010-03-31 EP disclosed
US-20090023902-A1 Method for the extraction of intracellular proteins from a fermentation broth DOW GLOBAL TECHNOLOGIES LLC 2009-01-22 US disclosed
EP-1720897-A2 METHOD FOR THE EXTRACTION OF INTRACELLULAR PROTEINS FROM A FERMENTATION BROTH The Dow Global Technologies Inc. (US) 2006-11-15 EP disclosed
WO-2005087791-A2 METHOD FOR THE EXTRACTION OF INTRACELLULAR PROTEINS FROM A FERMENTATION BROTH DOW GLOBAL TECHNOLOGIES INC. (US) 2005-09-22 WO disclosed