Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.48 |
| ▸ | BRD2 | P25440 | 9/20 | 0.48 |
| ▸ | BRD3 | Q15059 | 9/20 | 0.48 |
| ▸ | CCL2 | P13500 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TAF1 | P21675 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | BRWD1 | Q9NSI6 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13723764 | 1.00 | BRD4 (0.48) | BRD4BRD2BRD3CCL2TRIM24 | |
| SCHEMBL15437553 | 0.92 | BRD4 (0.53) | BRD4BRD2BRD3CCL2TRIM24 | |
| SCHEMBL15437234 | 0.90 | BRD4 (0.59) | BRD4BRD2BRD3CCL2TRIM24 | |
| SCHEMBL15437321 | 0.89 | BRD4 (0.62) | BRD4BRD2BRD3CCL2TRIM24 | |
| SCHEMBL13724338 | 0.88 | BRD4 (0.62) | BRD4BRD2BRD3CCL2TRIM24 | |
| SCHEMBL15437363 | 0.86 | BRD4 (0.63) | BRD4BRD2BRD3CCL2TRIM24 | |
| SCHEMBL15437262 | 0.86 | BRD4 (0.49) | BRD4BRD2BRD3CCL2TRIM24 | |
| SCHEMBL13723319 | 0.86 | BRD4 (0.49) | BRD4BRD2BRD3CCL2TRIM24 | |
| SCHEMBL15437592 | 0.86 | BRD4 (0.50) | BRD4BRD2BRD3TRIM24CYP3A4 | |
| SCHEMBL15437187 | 0.84 | BRD4 (0.60) | BRD4BRD2BRD3CCL2TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168213-A1 | TETRAHYDROQUINOLINE DERIVATIVES USEFUL AS BROMODOMAIN INHIBITORS | Glaxosmithkline LLC (US) | 2017-05-17 | — | — | EP | disclosed |