Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL944020 | 0.78 | TYR (0.44) | TYRLMNAALDH1A1MAPTPKM | |
| SCHEMBL2279013 | 0.78 | MCL1 (0.53) | TYRLMNAALDH1A1HTTMCL1 | |
| SCHEMBL104124 | 0.76 | TYR (0.58) | TYRLMNAALDH1A1HTTIDO1 | |
| SCHEMBL4556108 | 0.76 | SLC6A4 (0.52) | TYRALDH1A1HTT | |
| SCHEMBL10012057 | 0.76 | HTT (0.44) | TYRLMNAALDH1A1MAPTPKM | |
| SCHEMBL13831900 | 0.75 | SMN1; SMN2 (0.60) | TYRLMNAALDH1A1MAPTPKM | |
| SCHEMBL2022129 | 0.74 | TYR (0.41) | TYRLMNAALDH1A1MAPTPKM | |
| SCHEMBL21155778 | 0.74 | TYR (0.41) | TYRLMNAALDH1A1MAPTPKM | |
| SCHEMBL6366693 | 0.74 | HTT (0.43) | TYRALDH1A1HTTMCL1BCL2 | |
| SCHEMBL11312641 | 0.74 | TYR (0.41) | TYRLMNAALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167887-B1 | ARYL AMINE SUBSTITUTED QUINOXALINE USED AS ANTICANCER DRUGS | CHEN KUENFENG (TW) | 2021-03-24 | — | — | EP | disclosed |
| EP-3167887-A1 | ARYL AMINE SUBSTITUTED QUINOXALINE USED AS ANTICANCER DRUGS | Chen, Kuenfeng (TW) | 2017-05-17 | — | — | EP | disclosed |