Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10105843 | 0.94 | BRAF (1.00) | BRAF | |
| SCHEMBL10105348 | 0.93 | BRAF (1.00) | BRAF | |
| SCHEMBL10105282 | 0.91 | BRAF (1.00) | BRAF | |
| SCHEMBL18873757 | 0.91 | BRAF (0.88) | BRAF | |
| SCHEMBL10105392 | 0.91 | BRAF (1.00) | BRAF | |
| SCHEMBL10105294 | 0.90 | BRAF (1.00) | BRAF | |
| SCHEMBL10105407 | 0.90 | BRAF (1.00) | BRAF | |
| SCHEMBL10105316 | 0.87 | BRAF (1.00) | BRAF | |
| SCHEMBL18873758 | 0.86 | BRAF (0.85) | BRAF | |
| SCHEMBL18874163 | 0.85 | BRAF (0.88) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350083-B1 | PYRIMIDO[5,4-D]PYRIMIDINES AS CELL PROLIFERATION INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2017-05-17 | — | — | EP | disclosed |