Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18874346 | 0.91 | BRAF (0.62) | BRAF | |
| SCHEMBL18874303 | 0.86 | BRAF (0.62) | BRAF | |
| SCHEMBL18874027 | 0.83 | BRAF (0.64) | BRAF | |
| SCHEMBL18873774 | 0.83 | BRAF (0.66) | BRAF | |
| SCHEMBL18874359 | 0.82 | BRAF (0.57) | BRAF | |
| SCHEMBL18874150 | 0.81 | BRAF (0.62) | BRAF | |
| SCHEMBL18873746 | 0.78 | BRAF (0.70) | BRAF | |
| SCHEMBL10105879 | 0.76 | BRAF (1.00) | BRAF | |
| SCHEMBL10105878 | 0.76 | BRAF (0.76) | BRAF | |
| SCHEMBL10105888 | 0.76 | BRAF (0.86) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350083-B1 | PYRIMIDO[5,4-D]PYRIMIDINES AS CELL PROLIFERATION INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2017-05-17 | — | — | EP | disclosed |