Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064211 | 0.81 | IDO1 (0.54) | IDO1PDE2AMAOBDAOTAAR1 | |
| SCHEMBL13021064 | 0.81 | IDO1 (0.54) | IDO1PDE2ADAOTAAR1CA1 | |
| SCHEMBL11910682 | 0.81 | TRPV1 (0.44) | IDO1PDE2ATRPV1DAOKIF11 | |
| SCHEMBL20472553 | 0.79 | IDO1 (0.61) | IDO1PDE2AMAOBDAOTAAR1 | |
| SCHEMBL3094588 | 0.79 | TRPV1 (0.41) | IDO1TRPV1MAOBDAOTAAR1 | |
| SCHEMBL12601634 | 0.79 | IDO1 (0.51) | IDO1PDE2ATRPV1MAOBDAO | |
| SCHEMBL12561550 | 0.78 | TAAR1 (0.41) | TAAR1SLC6A4 | |
| Hydrochloric Acid SCHEMBL5178051 | 0.78 | IDO1 (0.64) | IDO1MAOBTAAR1CA1CA2 | |
| SCHEMBL27546311 | 0.78 | IDO1 (0.54) | IDO1PDE2AMAOBDAOTAAR1 | |
| SCHEMBL14402687 | 0.77 | IDO1 (0.50) | IDO1PDE2ATRPV1MAOBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |