Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.66 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18873861 | 0.92 | LPAR1 (0.75) | LPAR1SIRT2POLBFFAR4CHRM5 | |
| SCHEMBL18874390 | 0.88 | LPAR1 (0.51) | LPAR1SIRT2ALOX5POLBHDAC1 | |
| SCHEMBL1561438 | 0.86 | LPAR1 (0.85) | LPAR1SIRT2MAPTMEN1ALOX12 | |
| SCHEMBL18874040 | 0.82 | LPAR1 (0.45) | LPAR1MAPTMEN1KMT2A | |
| SCHEMBL18873905 | 0.81 | LPAR1 (0.57) | LPAR1SIRT2POLBFFAR4CHRM5 | |
| SCHEMBL18874305 | 0.81 | LPAR1 (0.51) | LPAR1SIRT2ALOX5HDAC1HDAC2 | |
| SCHEMBL18874189 | 0.80 | LPAR1 (0.58) | LPAR1SIRT2MEN1KMT2AALOX5 | |
| SCHEMBL1561172 | 0.80 | LPAR1 (1.00) | LPAR1 | |
| SCHEMBL18874159 | 0.79 | LPAR1 (0.57) | LPAR1SIRT2POLBFFAR4CHRM5 | |
| SCHEMBL18874199 | 0.79 | LPAR1 (0.57) | LPAR1SIRT2POLBFFAR4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |