Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 7/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25958901 | 0.93 | MYC (0.61) | MYCMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL4626423 | 0.89 | MYC (0.62) | MYCMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL4626421 | 0.89 | MYC (0.62) | MYCMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8432822 | 0.88 | MYC (0.64) | MYCMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8432826 | 0.88 | MYC (0.64) | MYCMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL23080298 | 0.87 | MYC (0.60) | MYCMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8436903 | 0.87 | MYC (0.60) | MYCMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL4624239 | 0.87 | MYC (0.60) | MYCMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8436905 | 0.87 | MYC (0.60) | MYCMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL4624238 | 0.87 | MYC (0.60) | MYCMAPTL3MBTL1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145494-A1 | COMPOUNDS AND SYSTEMS FOR IMPROVING SIGNAL DETECTION | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-05-25 | — | — | US | disclosed |